GA0307 Itraconazole

Synonyms: Oriconazole; R51211; Sporanox; (+/-)-4-[4-[4-[4-[[(2R,4S)-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

Structure for Itraconazole (84625-61-6)

CAS: 84625-61-6

MF: C₃₅H₃₈Cl₂N₈O₄

MW: 705.63

Assay: 99.0 - 101.0 % (dried basis)

Availability: In stock

GA0307 Itraconazole

CAS: 84625-61-6 MF: C₃₅H₃₈Cl₂N₈O₄ MW: 705.63

Assay: 99.0 - 101.0 % (dried basis) | Availability: In stock | SDS | Specification

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Product Detail
Product Specification
Safety Information
Citations (2)

Glentham Code

GA0307

Product Categories

APIs Antibiotics Antimicrobials Antifungals

CAS RN

84625-61-6

MDL Number

MFCD00870168

Storage Temperature

+4°C

Shipping Temperature

Ambient

Harmonised Tariff Code

29349990

Physical Description

White or almost white powder

Identification

To pass test

Solubility (10% in Dichloromethane)

Clear, colourless solution

Residue on Ignition

≤ 0.1%

Loss on Drying

≤ 1.0%

Assay

99.0 - 101.0 % (dried basis)

Specification Version

1.1

Pictograms

Signal word

Warning

Hazard statements

H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
H336: May cause drowsiness or dizziness
H302: Harmful if swallowed

Precautionary statements

P280: Wear protective gloves/protective clothing/eye protection/face protection.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P301+P312: IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.

SDS Version

2.0

If you are publishing research using GA0307 please contact us to contribute to our list of citations.

Identification and Pharmaceutical Characterization of a New Itraconazole Terephthalic Acid Cocrystal
Machado Cruz R, Boleslavská T, Beránek J, Tieger E, Twamley B, Santos-Martinez MJ, Dammer O, Tajber L.
Pharmaceutics, 741, 12(8) (2020)

The crystallization of poorly soluble drug molecules with an excipient into new solid phases called cocrystals has gained a considerable popularity in the pharmaceutical field. In this work, the cocrystal approach was explored for a very poorly water soluble antifungal active, itraconazole (ITR); w… read more

Impact of polyethylene glycol polymers on the physicochemical properties and mucoadhesivity of itraconazole nanoparticles
Ricardo Machado Cruz, Maria Jose Santos-Martinez, Lidia Tajber
European Journal of Pharmaceutics and Biopharmaceutics, Pages 57-67, 144 (2019)

Itraconazole (ITR) is a broad-spectrum antifungal drug with a very low solubility. In this work, the application of a heat induced evaporative antisolvent nanoprecipitation process yielded disordered nanoparticles (NPs) of ITR. The inclusion of different types of poly(ethylene glycol) (PEG) allowed… read more

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Certificate of Analysis

Example COA

Packaging Description For GA0307-1G

Description: 7ml glass vial with black screw cap (+50ml plastic screw pot - 50S)

Material: Clear glass vial. Black plastic cap.

Dimensions: 20 x 20 x 42 (mm)

Nominal volume: 7 (ml)

UN certified: No

If you would like any further details, please call us on +44 (0) 1225 667798 or send us an e-mail.

Packaging Description For GA0307-5G

Description: 15ml amber glass bottle with 28mm neck + 28mm blue cap with PTFE wad

Material: Amber glass

Dimensions: 32 x 32 x 53 (mm)

Nominal volume: 15 (ml)

UN certified: No

Weight: 44.085 g

If you would like any further details, please call us on +44 (0) 1225 667798 or send us an e-mail.

Stock Level Information

Our stock availability is calculated based on the quantity that we have in stock.

If a number of stock units is given in orange, we have enough material in smaller packs or in bulk to re-pack into these larger units.

This would not affect the dispatch date displayed.

For any questions or to check our stock, please call us on +44 (0) 1225 667798 or send us an e-mail.

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GA0307 Itraconazole

GA0307 Itraconazole

CAS: 84625-61-6 MF: C₃₅H₃₈Cl₂N₈O₄ MW: 705.63

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GA0307 Itraconazole

GA0307 Itraconazole

CAS: 84625-61-6 MF: C35H38Cl2N8O4 MW: 705.63

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CAS: 84625-61-6 MF: C₃₅H₃₈Cl₂N₈O₄ MW: 705.63