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GX7542 Cephalotaxine

Synonyms: [1S-(1α,3aS*,14bβ)]-1,5,6,8,9,14b-Hexahydro-2-methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol; (-)-Cephalotaxine; NSC 128487; NSC 245454
Structure for Cephalotaxine (24316-19-6)
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Large structure for Cephalotaxine (24316-19-6)

Structure for Cephalotaxine (24316-19-6)

CAS: 24316-19-6

MF: C18H21NO4

MW: 315.36

Purity (TLC): ≥ 97%

Availability: In stock

GX7542 Cephalotaxine

Synonyms: [1S-(1α,3aS*,14bβ)]-1,5,6,8,9,14b-Hexahydro-2-methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol; (-)-Cephalotaxine; NSC 128487; NSC 245454

CAS: 24316-19-6 MF: C18H21NO4 MW: 315.36

Purity (TLC): ≥ 97%    |    Availability:  In stock    |    SDS    |    Specification
Code
Packaging
Dispatches
Size
No. Units
Price (USD)
GX7542-5MG
5
4th June 2023
5mg
$97.10
GX7542-10MG
2
4th June 2023
10mg
$158.70
GX7542
BULK
Cephalotaxine is a benzazepine alkaloid found in Cephalotaxus harringtonia, an evergreen shrub from Japan. It is an antiviral agent that has potential applications in the treatment of hepatitis B. Cephalotaxine is also an antitumour agent that works by inhibiting protein translation.
Glentham Code
GX7542
CAS RN
24316-19-6
Storage Temperature
+4°C
Shipping Temperature
Ambient
Harmonised Tariff Code
3822002099
Physical Description
White to off-white solid or powder
Identification (1H-NMR)
To conform to structure
Melting Point
≥ 125°C
Purity (TLC)
≥ 97%
Specification Version
1.0
Pictograms
SDS pictograms
Signal word
Warning
Hazard statements
H302: Harmful if swallowed.
H312: Harmful in contact with skin.
H332: Harmful if inhaled.
Precautionary statements
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
UN Number
UN1544 - 6.1 - PG III
SDS Version
1.0
If you are publishing research using GX7542 please contact us to contribute to our list of citations.
Anti-varicella-zoster virus activity of cephalotaxine esters in vitro
Jung-Eun Kim, Yoon-Jae Song
Journal of Microbiology, Pages 74, 57 (2019)

Harringtonine (HT) and homoharringtonine (HHT); alkaloid esters isolated from the genus Cephalotaxus, exhibit antitumor activity. A semisynthetic HHT has been approved for treatment of chronic myelogenous leukemia. In addition to antileukemic activity, HT and HHT are reported to possess potent anti… read more

Ester alkaloids from Cephalotaxus interfere with the 2’3’-cGAMP-induced type I interferon pathway in vitro
Gayoung Park, Sun Yeou Kim, Yoon-Jae Song
PLOS ONE, e0182701, 12(8) (2017)

Dysregulated activation of the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway by self-DNA contributes to interferonopathy and promotes autoimmune diseases. To identify potential suppressors of STING-induced type I interferon (IFN) induction, ethanol extracts of medicina… read more

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Specification View
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Certificate of Analysis
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Structure for Cephalotaxine (24316-19-6)

GX7542
24316-19-6

Cephalotaxine

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Packaging Description For GX7542-5MG

Description: 2ml glass vial with plastic stopper (+50ml plastic screw pot - 50S)

Material: glass vial with plastic push fit stopper

Dimensions: 0 x 0 x 0 (mm)

Nominal volume: 2 (ml)

UN certified: No

Weight: 2.552 g

If you would like any further details, please call us on +44 (0) 1225 667798 or send us an e-mail.

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Packaging Description For GX7542-10MG

Description: 2ml glass vial with plastic stopper (+50ml plastic screw pot - 50S)

Material: glass vial with plastic push fit stopper

Dimensions: 0 x 0 x 0 (mm)

Nominal volume: 2 (ml)

UN certified: No

Weight: 2.552 g

If you would like any further details, please call us on +44 (0) 1225 667798 or send us an e-mail.

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Stock Level Information

Our stock availability is calculated based on the quantity that we have in stock.

If a number of stock units is given in orange, we have enough material in smaller packs or in bulk to re-pack into these larger units.

This would not affect the dispatch date displayed.

For any questions or to check our stock, please call us on +44 (0) 1225 667798 or send us an e-mail.