GX7542 Cephalotaxine

Synonyms: [1S-(1α,3aS*,14bβ)]-1,5,6,8,9,14b-Hexahydro-2-methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol; (-)-Cephalotaxine; NSC 128487; NSC 245454

Structure for Cephalotaxine (24316-19-6)

Structure for Cephalotaxine (24316-19-6)

CAS: 24316-19-6

MF: C₁₈H₂₁NO₄

MW: 315.36

Purity (TLC): ≥ 97%

Availability: In stock

GX7542 Cephalotaxine

Synonyms: [1S-(1α,3aS*,14bβ)]-1,5,6,8,9,14b-Hexahydro-2-methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol; (-)-Cephalotaxine; NSC 128487; NSC 245454

CAS: 24316-19-6 MF: C₁₈H₂₁NO₄ MW: 315.36

Purity (TLC): ≥ 97% | Availability: In stock | SDS | Specification

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Cephalotaxine is a benzazepine alkaloid found in Cephalotaxus harringtonia, an evergreen shrub from Japan. It is an antiviral agent that has potential applications in the treatment of hepatitis B. Cephalotaxine is also an antitumour agent that works by inhibiting protein translation.

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Product Specification
Safety Information
Citations (2)

Glentham Code

GX7542

CAS RN

24316-19-6

Storage Temperature

+4°C

Shipping Temperature

Ambient

Harmonised Tariff Code

3822002099

Physical Description

White to off-white solid or powder

Identification (1H-NMR)

To conform to structure

Melting Point

≥ 125°C

Purity (TLC)

≥ 97%

Specification Version

1.0

Pictograms

Signal word

Warning

Hazard statements

H302: Harmful if swallowed.
H312: Harmful in contact with skin.
H332: Harmful if inhaled.

Precautionary statements

P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.

UN Number

UN1544 - 6.1 - PG III

SDS Version

1.0

If you are publishing research using GX7542 please contact us to contribute to our list of citations.

Anti-varicella-zoster virus activity of cephalotaxine esters in vitro
Jung-Eun Kim, Yoon-Jae Song
Journal of Microbiology, Pages 74, 57 (2019)

Harringtonine (HT) and homoharringtonine (HHT); alkaloid esters isolated from the genus Cephalotaxus, exhibit antitumor activity. A semisynthetic HHT has been approved for treatment of chronic myelogenous leukemia. In addition to antileukemic activity, HT and HHT are reported to possess potent anti… read more

Ester alkaloids from Cephalotaxus interfere with the 2’3’-cGAMP-induced type I interferon pathway in vitro
Gayoung Park, Sun Yeou Kim, Yoon-Jae Song
PLOS ONE, e0182701, 12(8) (2017)

Dysregulated activation of the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway by self-DNA contributes to interferonopathy and promotes autoimmune diseases. To identify potential suppressors of STING-induced type I interferon (IFN) induction, ethanol extracts of medicina… read more

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Packaging Description For GX7542-5MG

Description: 2ml glass vial with plastic stopper (+50ml plastic screw pot - 50S)

Material: glass vial with plastic push fit stopper

Dimensions: 0 x 0 x 0 (mm)

Nominal volume: 2 (ml)

UN certified: No

Weight: 2.552 g

If you would like any further details, please call us on +44 (0) 1225 667798 or send us an e-mail.

Packaging Description For GX7542-10MG

Description: 2ml glass vial with plastic stopper (+50ml plastic screw pot - 50S)

Material: glass vial with plastic push fit stopper

Dimensions: 0 x 0 x 0 (mm)

Nominal volume: 2 (ml)

UN certified: No

Weight: 2.552 g

If you would like any further details, please call us on +44 (0) 1225 667798 or send us an e-mail.

Stock Level Information

Our stock availability is calculated based on the quantity that we have in stock.

If a number of stock units is given in orange, we have enough material in smaller packs or in bulk to re-pack into these larger units.

This would not affect the dispatch date displayed.

For any questions or to check our stock, please call us on +44 (0) 1225 667798 or send us an e-mail.

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GX7542 Cephalotaxine

GX7542 Cephalotaxine

CAS: 24316-19-6 MF: C₁₈H₂₁NO₄ MW: 315.36

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GX7542 Cephalotaxine

GX7542 Cephalotaxine

CAS: 24316-19-6 MF: C18H21NO4 MW: 315.36

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Packaging Description For GX7542-10MG

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CAS: 24316-19-6 MF: C₁₈H₂₁NO₄ MW: 315.36