Physical Description
Colourless or brownish viscous liquid
Assay
99.0 - 101.0 % (anhydrous)
Solubility
Soluble in water, miscible with anhydrous ethanol
Appearance of Solution
1g/10ml in water, Colour: < Y5, BY5 or R5
Specific Optical Rotation
-140 - -152 ° (1g/50ml in ethanol)
Impurities
Nicotine-trans-N-oxide: ≤ 0.2%
Nicotine-cis-N-oxide: ≤ 0.2%
Total Nicotine-N-oxides: ≤ 0.3%
Any Unspecified Impurity
≤ 0.1%
Pharmacopoeia Specification(s)
EP
Specification Version
1.0
Hazard statements
H301: Toxic if swallowed.
H310: Fatal in contact with skin.
H411: Toxic to aquatic life with long lasting effects.
Precautionary statements
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
UN Number
UN1654 - 6.1 - PG II
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